hrp0082p2-d2-298 | Bone (1) | ESPE2014

Zoledronic Acid for Management of Osteopenia of Prematurity and Associated Ventilator Dependency

White Mary , Pellicano Anastasia , Zacharin Margaret , Simm Peter

Background: The effect of bisphosphonates in patients with severe osteopenia of prematurity is unknown in terms of either fracture prevention or long-term safety. A 6-month-old male infant born at 24+2 weeks gestation was referred for consideration of bisphosphonate therapy in the management of severe osteopenia of prematurity. The neonatal course included chronic lung disease requiring four courses of corticosteroids. Despite optimal calcium, phosphate and vitamin D supplemen...